As debate in the medical press continues on the likely mechanism of action and efficacy of drugs that might slow or protect against aortic dilatation in patients with Marfan syndrome, Professors Tom Treasure, John Pepper and Raad Mohiaddin have written to the Editor of the New England Journal of Medicine to draw attention to the benefit to patients of the Personalised External Aortic Root Support as an alternative to replacement when surgery is indicated. You can read this correspondence here.