A further two patients have been included in the clinical trial of the Exovasc® Personalised External Aortic Root Support in the last seven weeks and a further patient is scheduled for surgery in the coming week. Progress in the trial is dependent on the number of suitable patients with Marfan syndrome who are referred to Professor John Pepper at the Royal Brompton Hospital and are suitable to receive their ExoVasc® Personalised External Aortic Root Supports, and we are encouraged to add several further patients within a short time. The experience with all of the recent cases is that surgery is relatively short and patients do not require cardiopulmonary bypass.